Pain

Is My Patient Suffering Complex Regional Pain Syndrome?

Is My Patient Suffering Complex Regional Pain Syndrome? – MM1409

Complex regional pain syndrome (CRPS) is a chronic pain condition mostly affecting one of the limbs (arms, legs, hands or feet), usually after an injury or trauma to that limb. CRPS is thought to be caused by damage to or malfunction of the peripheral and central nervous system. Although most cases of CRPS are triggered by an injury, the resulting pain is far more severe and long-lasting than normal.

Modern Medicine – September 2014

Percutaneous Intervertebral Disc Decompression for Pain Management

Percutaneous Intervertebral Disc Decompression for Pain Management – MM1404

For a very specifically defined group of patients with contained intervertebral disc protrusions, there is an option called nucleoplasty or plasma disc decompression. Nucleoplasty is a procedure for percutaneous disc decompression based on a minimally invasive interventional procedure.

Modern Medicine – April 2014

The Physiology of Chronic Pain The Role of the Inhibitory Interneuron

The Physiology of Chronic Pain The Role of the Inhibitory Interneuron – MM1401

As described in the original article in May 2013, central sensitisation of the dorsal horn cells with facilitated pain processing and transmission can occur after nerve injury, deafferentation of the spinal cord (amputation or nerve section) or due to afferent barrage.
As a result, anatomical and neuro-chemical changes can occur within the central nervous system (CNS) that can persist long after the injury has healed.
This ‘CNS plasticity’ may play an important role in the evolution of chronic, neuropathic pain. The sensitisation of neurons that occurs within the dorsal horn results in spontaneous activity of the dorsal horn neurons, a decreased threshold and an increased responsivity to afferent input, and cell death in the spinal dorsal horn. The cells that die are the inhibitory interneurons.

Modern Medicine – January 2014

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