The Atypical Opioids Buprenorphine, tramadol and tapentadolmorphine
There are many differences between conventional and atypical opioids, including different efficacies, adverse effects and toxicities, as well as risk of abuse. These factors should be considered when prescribing opioids for chronic pain conditions. Atypical opioids differ from conventional opioids as they do not rely exclusively on mu-receptor agonism for their analgesic effect.
Modern Medicine â Issue 5 2019
Treatment of Patients with Opioid Dependence â MM1611
The prevalence of opioid dependence is growing with the increased use of pharmaceutical opioids. A number of effective interventions exist for patients with opioid dependence, including withdrawal services, opioid substitution treatment and psychosocial interventions, supported by self-help groups and harm-reduction services. Although historically most opioid-dependent users have used illicit opioids such as heroin as their primary drug, doctors are more often encountering patients who either misuse pharmaceutical opioid medications not prescribed for them or, alternatively, develop dependence on opioid medications used in the treatment of chronic pain.
Modern Medicine â November 2016
Use of Opioids in Chronic Noncancer Pain â MM1505
Opioids play a much smaller role in the management of chronic noncancer pain than they do in that of severe acute pain and cancer pain. They are beneficial in a small subset of patients with chronic noncancer pain but there are pharmacological, psychological and societal concerns about their current widespread use for this indication.
Modern Medicine â May 2015
