Wet Macular Degeneration, a Leading Cause of Blindness – MM1703
AMD is a multi-faceted condition that affects the central retina, which ultimately leads to blindness in millions of
people worldwide. The pathophysiology and risk factors for AMD are complex and the symptoms manifest in
multiple related but distinct forms. It is well-established that vascular endothelial growth
factor (VEGF) plays a major role in the neovascular or exudative form of AMD by aiding in the induction of
angiogenesis and enhancing vascular permeability. Consequently, intravitreal injections with medications
targeting VEGF have become the standard of care for exudative AMD.
Modern Medicine – February 2017
