Disrupted Sleep Precedes Alzheimer Onset
Disturbances in the sleep–wake cycle and circadian rhythms are common symptoms of Alzheimer Disease
(AD), and they have generally been considered as late consequences of the neurodegenerative processes.
Recent evidence demonstrates that sleep–wake and circadian disruption often occur early in the course of
the disease and may even precede the development of cognitive symptoms.
Modern Medicine – August 2017
