Putting the Brakes on Asthma Airway Inflammation in Children
Asthma is the most common chronic disease of childhood and its prevalence has substantially increased worldwide, particularly in pre-school children. Chronic inflammation and smooth muscle dysfunction are consistent features of asthma pathophysiology, responsible for disease progression and airway remodelling. Montelukast, a cysteinyl leukotriene 1 receptor antagonist, is indicated as an alternative treatment in paediatric asthma management and to relieve symptoms of seasonal allergies.
Modern Medicine β Issue 1 2022