Epinephrine, First-line Treatment for High-risk Allergic Reactions – MM1409
Any allergic reaction, including the most extreme form, anaphylaxis, occurs when the body’s immune system reacts inappropriately in response to the presence of a substance that is wrongly perceived as a threat. Anaphylaxis is an acute, potentially life-threatening hypersensitivity reaction, involving the release of mediators from mast cells, basophils and recruited inflammatory cells. Anaphylaxis is defined according to a number of signs and symptoms occurring alone or in combination within minutes or up to a few hours after exposure to a provoking agent.
Modern Medicine – September 2014
