Hyperconnectivity Seen in Juvenile Myoclonic Epilepsy – MM1502
Juvenile myoclonic epilepsy (JME) is the most common idiopathic (presumed genetic) generalised epilepsy (IGE) syndrome and represents five to 10% of all epilepsies. It is characterised by an age-related onset of upper limb myoclonic seizures in the mid-teens, followed in the majority of cases by generalised tonic–clonic seizures. There is increasing evidence of cognitive dysfunction in these patients, with deficits reported on tests of frontal lobe function.
Modern Medicine – February 2015